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Pioneering AI-integrated point-of-care diagnostics at the intersection of nanotechnology, machine learning, and clinical medicine. Developing solid-state nanopore biosensors for early detection of Alzheimer's and cancer.

I am a nanobiotechnologist, materials scientist, and biomedical engineer pioneering AI-integrated point-of-care diagnostics at the intersection of nanotechnology, machine learning, and clinical medicine. With a strong foundation in physics and expertise in nanomaterials fabrication, I develop novel biosensing platforms that push the boundaries of early disease detection.
My research program develops solid-state nanopore biosensors for early detection of neurodegenerative diseases and cancer, achieving label-free protein identification with 88.7% accuracy through innovative fusion of single-molecule sensing and machine learning. This work has been featured in over 100 international media outlets.
With demonstrated success in translational research, including partnerships with Thaum Pty Ltd for early diagnostics of Alzheimer's and collaborations with ACT Health and Rio-Tinto on environmental health monitoring, I bridge fundamental biophysics and nanoscience with biomedical applications. My materials science background enables precise control over nanopore fabrication using ion irradiation, chemical etching, and advanced thin-film deposition techniques.
International award for outstanding early-career research
Royal Society of New South Wales
International Phase (USA, Europe, China, Japan)
Research Fellow (Level B)
Australian National University
Solid-State Nanopore Membranes
ANU, 2018-2024
Canberra, Australia
Research School of Physics
Interested in research partnerships or student supervision opportunities.
Get in touchDeveloping AI-integrated point-of-care diagnostics at the intersection of nanotechnology, machine learning, and clinical medicine.
Our research combines cutting-edge nanopore sensing with advanced machine learning to revolutionize disease detection and personalized medicine.
Neural networks trained on millions of nanopore signals for pattern recognition
Industry-leading protein identification accuracy from single molecules
GPU-accelerated processing for instant biomarker detection
Machine learning models for early disease detection and prognosis
High-bandwidth nanopore signals
Amplitude, duration, shape analysis
Deep learning classification
Biomarker identification
Selected highlights from my peer-reviewed research contributions
S. Dutt, L. Lai, B.I. Karawdeniya, Y.M. Bandara, A. J. Clulow, V. Gopalan, P. Kluth
Nucleic Acids Research (2025)
Y. M. Bandara, S. Dutt, B. Karawdeniya, J. Saharia, P. Kluth and A. Tricoli
Small Methods 8 (12) 2400045 (2024)
S. Dutt, H. Shao, B.I. Karawdeniya, Y.M. Bandara, E. Daskalaki, H. Suominen, P. Kluth
Small Methods 7, 11:2300676 (2023)
S. Dutt, B.I. Karawdeniya, Y.M. Bandara, N. Afrin, P. Kluth
Analytical Chemistry 95, 13 (2023): 5754-5763 (2023)
Research featured in 100+ international media outlets
News Medical
2023
By employing advanced filtration techniques and harnessing our nanopore platform, combined with our intelligent machine learning algorithms, we may be able to identify even the most elusive proteins.
ABC Radio
2023
If that person can find out their risk level that far in advance, then it gives them plenty of time to start making positive lifestyle changes...
ANU News
2021
We're the first to quantify the shape of the nanopores, using small-angle X-ray scattering at the Australian Synchrotron in Melbourne.
Research School of Physics
Australian National University
Leading nanopore biosensor development, secured >$500K funding, supervising PhD students
Research School of Physics
Australian National University
Developed AI-integrated nanopore biosensors for early disease detection
Development of functional solid-state nanopore membranes
Australian National University
Thesis: Development and investigation of functional solid-state nanopore membranes
University Gold Medallist (Rank 1)
Guru Nanak Dev University, India
GPA: 9.75/10
University Gold Medallist (Rank 1)
Guru Nanak Dev University, India
GPA: 9.92/10
Working with leading institutions and industry partners worldwide
Whether you're interested in collaboration, seeking a PhD position, or exploring industry partnerships, I'd love to hear from you.
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Collaborate on projects
Partnership opportunities